ELEMENTS OF NEUROCHEMISTRY: CHE 580

Professor Allan Butterfield

Have you ever wondered how the brain actually works? What are the chemical principles that underlie brain neurochemistry? What happens when this brain chemistry goes awry? If these questions are of interest to you, sign up during Fall registration for my course.

This course is a major field option for undergraduates and an advanced course for graduate students.

Topics to be covered :

Neurocellular Membrane Structure and Functions

Neurolipids

Membrane Transport

Electrical Excitability and Ion Channels

Intracellular Trafficking

Synaptic Transmission and Cellular Signaling: Acetylcholine;

Glutamate

Intracellular Signaling: G-proteins; Phosphoinositides; Cyclic Nucleotides;

Ca 2+; Phosphorylation of Ser, Thr, Tyr

Energy Metabolism in the Brain

Apoptosis and Necrosis: Role of Mitochondria

Neurochemistry of Inherited and Neurodegenerative Diseases

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Updated 6/2/08