Practice Problem Four

Submit this for 2 pts. credit.
Examine our recent notes on stereocontrol in the Aldol reaction. See pertinent reviews.

  1. Retrosynthetically analyze molecule A down to commercially available reactants. If you are lost, retrosynthetic analysis of molecule B before you analyze A will help you.
  2. Now devise a forward synthesis detailing every step. You should provide a reference for each step.
  3. Retrosynthetically analyze molecule B down to commercially available reactants.
  4. Retrosynthetically analyze molecule C down to commercially available reactants.
  5. Choose molecule B or C and detail how you would make it enantiospecifically with a chiral auxiliary.