Publication

(To use DOI links, go to http://dx.doi.org/ then enter the doi provided for the paper of interest.)

Publications in 2008

1. Redox tuning over almost 1 V in a structurally-conserved active site: lessons from superoxide dismutase.   A.-F.Miller (2008)   Acc. Chem. Res. 41 (4): 501-510. http://pubs.acs.org/cgi-bin/article.cgi/achre4/2008/41/i04/pdf/ar700192d.pdf

2. Hydrogen Bond-Free Flavin Redox Properties: Managing Flavins in Extreme Aprotic Solvents.   J. F. Cerda, R. L. Koder, B. R. Lichtenstein, C. M. Moser, A.-F.Miller, and P. L. Dutton (2008)   Org. Biomol. Chem. In Press. DOI: 10.1039/ B801952E

3. Carbon Centered Radicals in Isolated Soy Proteins   W. L. Boatright, M.S. Jahan, B.M. Walters, A.-F. Miller, D. Cui, E.J. Hustedt and Q. Lei (2008)   J Food Science, 73(3): C222-226. doi: 10.1111/j.1750-3841.2008.00693.x

4. Spectroscopic and Computational Insights into Second-Sphere Amino-Acid Tuning of Substrate Analogue/Active-Site Interactions in Iron(III) Superoxide Dismutase.   L. E. Grove, J. Xie, E. Yikilmaz, A. Karapetyan, A.-F. Miller, and T. C. Brunold (2008)   Inorg. Chem In Press. **

5. Spectroscopic and Computational Insights into Second-Sphere Contributions to Redox Tuning in Eschericia coli Iron Superoxide Dismutase.   L. E. Grove, J. Xie, E. Yikilmaz, A.-F. Miller, and T. C. Brunold (2008)   Inorg. Chem In Press. **

Publications in 2007

1. How can a single second sphere amino acid change cause a reduction midpoint potential change of hundreds of mV ?   E. Yikilmaz, J. Porta, L. Grove, A. Vahedi-Faridi, Y. Bronshteyn, T. C. Brunold, G. E. O. Borgstahl and A.-F. Miller (2007)   J. Am. Chem. Soc. 129: 9927-9940. http://pubs.acs.org/cgi-bin/article.cgi/jacsat/2007/129/i32/pdf/ja069224t.pdf

2. A flavin analogue with improved solubility in organic solvents.   R. L. Koder, Jr., B. R. Lichtenstein, J. F. Cerda, A.-F. Miller and P. L. Dutton (2007)   Tet. Lett. 48: 5517-5520. doi:10.1016/j.tetlet.2007.05.165

Publications in 2006

1. The Crucial Importance in Chemistry in the Structure-Function Link: Manipulating H-Bonding in Fe-Superoxide Dismutase.   E. Yikilmaz, D. W. Rodgers and A.-F. Miller, (2006)   Biochemistry 45(4) 1151-1161. http://pubs.acs.org/cgi-bin/article.cgi/bichaw/2005/44/i05/pdf/bi048639t.pdf

2. Evidence for polyproline II helical structure in short polyglutamine tracts.   B. W. Chellgren, A.-F. Miller and T. P. Creamer (2006)   Journal of Molecular Biology 36 362-371. doi:10.1016/j.jmb.2006.06.044

3. ¹⁵N Solid-State NMR provides a sensitive probe of oxidized flavin reactive sites.   R. L. Koder, Jr., J. D. Walsh, M. S. Pometun, P. L. Dutton, R. J. Wittebort and A.-F. Miller (2006)   J. Am. Chem. Soc. 128(47) 15200-15208 http://pubs.acs.org/cgi-bin/article.cgi/jacsat/2006/128/i47/pdf/ja0648817.pdf

Publications in 2005

1. Anion Binding Properties of Reduced and Oxidized Iron-Containing Superoxide Dismutase Reveal No Requirement for Tyrosine 34. A.-F. Miller,   David L. Sorkin, K. Padmakumar (2005).  Biochemistry, 44, 5969-5981. [pdf].

2. Probing the Geometric and Electronic Structures of the Low Temperature Azide Adduct and the Product-Inhibited Form of Oxidized Manganese Superoxide Dismutase.   T. A. Jackson, A. Karapetyan, A.-F. Miller and T. C. Brunold, (2005) Biochemistry 44(5) 1504-1520. http://pubs.acs.org/cgi-bin/article.cgi/bichaw/2005/44/i05/pdf/bi048639t.pdf

Publications in and before 2004

1. Superoxide dismutases: active sites that save, but a protein that kills.     Miller, Anne-Frances.    Current Opinion in Chemical Biology  (2004),  8(2),  162-168. [pdf]

2. Spectroscopic and computational study of a non-heme iron {Fe-NO}7 system: Exploring the geometric and electronic structures of the nitrosyl adduct of iron superoxide dismutase.     Jackson, Timothy A.; Yikilmaz, Emine; Miller, Anne-Frances; Brunold, Thomas C.    Journal of the American Chemical Society  (2003),  125(27),  8348-8363.[pdf] 

3. Flavin reduction potential tuning by substitution and bending.     Walsh, Joseph D.; Miller, Anne-Frances.   THEOCHEM  (2003),  623  185-195.[pdf] 

4. Proton-coupled electron transfer in Fe-superoxide dismutase and Mn-superoxide dismutase.     Miller, Anne-Frances; Padmakumar, K.; Sorkin, David L.; Karapetian, A.; Vance, Carrie K.     Journal of Inorganic Biochemistry  (2003),  93(1-2),  71-83. [pdf]

5. NMR Shieldings and Electron Correlation Reveal Remarkable Behavior on the Part of the Flavin N5 Reactive Center.     Walsh, Joseph D.; Miller, Anne-Frances.      Journal of Physical Chemistry B  (2003),  107(3),  854-863. [pdf]

6. Comparison and Contrasts between the Active Site pK of Mn-Superoxide Dismutase and Those of Fe-Superoxide Dismutase.     Maliekal, James; Karapetian, Anush; Vance, Carrie; Yikilmaz, Emine; Wu, Qiang; Jackson, Timothy; Brunold, Thomas C.; Spiro, Thomas G.; Miller, Anne-Frances.      Journal of the American Chemical Society  (2002),  124(50),  15064-15075. [pdf]

7. Flavin Thermodynamics Explain the Oxygen Insensitivity of Enteric Nitroreductases.     Koder, Ronald L.; Haynes, Chad A.; Rodgers, Michael E.; Rodgers, David W.; Miller, Anne-Frances.     Biochemistry  (2002),  41(48),  14197-14205. [pdf]

8. Spectroscopic and Computational Studies on Iron and Manganese Superoxide Dismutases: Nature of the Chemical Events Associated with Active-Site pKs.     Jackson, Timothy A.; Xie, Juan; Yikilmaz, Emine; Miller, Anne-Frances; Brunold, Thomas C.      Journal of the American Chemical Society  (2002),  124(36),  10833-10845. [pdf]

9. Two-electron reduction of quinones by Enterobacter cloacae NAD(P)H:nitroreductase: quantitative structure-activity relationships.    Nivinskas, Henrikas; Staskeviciene, Sigita; Sarlauskas, Jonas; Koder, Ronald L.; Miller, Anne-Frances; Cenas, Narimantas.    Archives of Biochemistry and Biophysics  (2002),  403(2),  249-258. [pdf]

10. Structures of nitroreductase in three states. Effects of inhibitor binding and reduction.     Haynes, Chad A.; Koder, Ronald L.; Miller, Anne-Frances; Rodgers, David W.    Journal of Biological Chemistry  (2002),  277(13),  11513-11520. [pdf]

11. Second-Sphere Contributions to Substrate-Analogue Binding in Iron(III) Superoxide Dismutase.     Xie, Juan; Yikilmaz, Emine; Miller, Anne-Frances; Brunold, Thomas C.    Journal of the American Chemical Society  (2002),  124(14),  3769-3774.[pdf] 

12. Hydrogen-Bond-Mediated Tuning of the Redox Potential of the Non-Heme Fe Site of Superoxide Dismutase.     Yikilmaz, Emine; Xie, Juan; Brunold, Thomas C.; Miller, Anne-Frances.    Journal of the American Chemical Society  (2002),  124(14),  3482-3483.[pdf]

13. Retro-nitroreductase, a putative evolutionary precursor to Enterobacter cloacae strain 96-3 nitroreductase.     Koder, Ronald L.; Oyedele, Omolara; Miller, Anne-Frances.      Antioxidants & Redox Signaling  (2001),  3(5),  747-755. [pdf]

14. Host-Guest Study of Left-Handed Polyproline II Helix Formation.     Kelly, Melissa A.; Chellgren, Brian W.; Rucker, Adam L.; Troutman, Jerry M.; Fried, Michael G.; Miller, Anne-Frances; Creamer, Trevor P.    Biochemistry  (2001),  40(48),  14376-14383. [pdf]

15. Novel Insights into the Basis for Escherichia coli Superoxide Dismutase's Metal Ion Specificity from Mn-Substituted FeSOD and Its Very High Em.     Vance, Carrie K.; Miller, Anne-Frances.    Biochemistry  (2001),  40(43),  13079-13087. [pdf]

16. Two-electron reduction of nitroaromatic compounds by Enterobacter cloacae NAD(P)H nitroreductase: description of quantitative structure-activity relationships.    Nivinskas, Henrikas; Koder, Ronald L.; Anusevicius, Zilvinas; Sarlauskas, Jonas; Miller, Anne-Frances; Cenas, Narimantas.      Acta Biochimica Polonica  (2000),  47(4),  941-949.[pdf] 

17. Quantitative Structure-Activity Relationships in Two-Electron Reduction of Nitroaromatic Compounds by Enterobacter cloacae NAD(P)H:Nitroreductase.     Nivinskas, Henrikas; Koder, Ronald L.; Anusevicius, Zilvinas; Sarlauskas, Jonas; Miller, Anne-Frances; Cenas, Narimantas.     Archives of Biochemistry and Biophysics  (2001),  385(1),  170-178. [pdf]

18. Mutational and spectroscopic studies of the significance of the active site glutamine to metal ion specificity in superoxide dismutase.    Schwartz, Aaron L.; Yikilmaz, Emine; Vance, Carrie K.; Vathyam, Surekha; Koder, Ronald L.; Miller, Anne-Frances.  Journal of Inorganic Biochemistry  (2000),  80(3-4),  247-256.[pdf] 

19. Amino acid-specific isotopic labeling and active site NMR studies of iron(II)- and iron(III)-superoxide dismutase from Escherichia coli.     Sorkin, David L.; Miller, Anne-Frances.      Journal of Biomolecular NMR  (2000),  17(4),  311-322.[pdf] 

20. Mapping the effects of metal ion reduction and substrate analog binding to Fe-superoxide dismutase by NMR spectroscopy.     Vathyam, Surekha; Byrd, R. Andrew; Miller, Anne-Frances.      Magnetic Resonance in Chemistry  (2000),  38(7),  536-542.[pdf]

21. Assignment of the backbone resonances of oxidized Fe-superoxide dismutase, a 42 kDa paramagnet-containing enzyme.     Vathyam, Surekha; Byrd, R. Andrew; Miller, Anne-Frances.      Journal of Biomolecular NMR  (1999),  14(3),  293-294.[pdf]

22. Mutagenesis studies of the FeSII protein of Azotobacter vinelandii: Roles of histidine and lysine residues in the protection of nitrogenases from oxygen damage. Jianrong Lou, Farhad Moshiri, Michael K. Johnson, Meghan E. Lafferty, David L. Sorkin, A.-F. Miller, and Robert J. Maier. Biochemistry  (1999) 38, 5563-5571.[pdf]

23. Parallel Polarization EPR Characterization of the Mn(III) Center of Oxidized Manganese Superoxide Dismutase.    Campbell, Kristy A.; Yikilmaz, Emine; Grant, Christopher V.; Gregor, Wolfgang; Miller, Anne-Frances; Britt, R. David.     Journal of the American Chemical Society  (1999),  121(19),  4714-4715.[ pdf]

24. Steady-state kinetic mechanism, stereospecificity, substrate and inhibitor specificity of Enterobacter cloacae nitroreductase.     Koder, Ronald L.; Miller, Anne-Frances.      Biochimica et Biophysica Acta  (1998),  1387(1-2),  395-405.[pdf] 

25. Overexpression, isotopic labeling, and spectral characterization of Enterobacter cloacae nitroreductase.     Koder, Ronald L.; Miller, Anne-Frances.      Protein Expression and Purification  (1998),  13(1),  53-60.[pdf] 

26. Spectroscopic Comparisons of the pH Dependencies of Fe-Substituted (Mn)Superoxide Dismutase and Fe-Superoxide Dismutase.     Vance, Carrie K.; Miller, Anne-Frances.       Biochemistry  (1998),  37(16),  5518-5527.[pdf]

27. A simple proposal that can explain the inactivity of metal-substituted superoxide dismutaes. C. K. Vance and A.-F. Miller  (1998)  120(3) 461-467.[pdf]

28. Mutation of Tyrosine 34 to Phenylalanine Eliminates the Active Site pK of Reduced Iron-Containing Superoxide Dismutase.     Sorkin, David L.; Duong, David K.; Miller, Anne-Frances.     Biochemistry  (1997),  36(27),  8202-8208. [pdf]

29. Superoxide dismutases: a molecular perspective.     Miller, Anne-Frances; Sorkin, David L.   Comments on Molecular and Cellular Biophysics  (1997),  9(1),  1-48.

30. Selective 15N labeling and direct observation by NMR of the active-site glutamine of Fe-containing superoxide dismutase.    Vance, Carrie K.; Kang, Young M.; Miller, Anne-Frances.      Journal of Biomolecular NMR  (1997),  9(2),  201-206. [pdf]

31. Spectroscopic measurement of a long-predicted active site pK in iron-superoxide dismutase from Escherichia coli.     Sorkin, David L.; Miller, Anne-Frances.      Biochemistry  (1997),  36(16),  4916-4924.[pdf] 

32. Measurement of the degree of coupled isotopic enrichment of different positions in an antibiotic peptide by NMR. Journal of magnetic resonance  (1997),  125, 120-131.[pdf]

33. Solution Structure of the MutT Enzyme, a Nucleoside Triphosphate Pyrophosphohydrolase.     Abeygunawardana, Chitrananda; Weber, David J.; Gittis, Apostolos G.; Frick, David N.; Lin, Jian; Miller, Anne-Frances; Bessman, Maurice J.; Mildvan, Albert S.    Biochemistry  (1995),  34(46),  14997-5005.[pdf] 

34. An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras.     Miller, Anne Frances; Halkides, Christopher J.; Redfield, Alfred G.    Biochemistry  (1993),  32(29),  7367-76. [pdf]

35. NMR studies of the conformational change in human N-p21ras produced by replacement of bound GDP with the GTP analog GTPgS.     Miller, Anne Frances; Papastavros, Mary Z.; Redfield, Alfred G.      Biochemistry  (1992),  31(42),  10208-16. [pdf]

36. The dependence on iron availability of allocation of iron to nitrogenase components in Klebsiella pneumoniae and Escherichia coli.     Miller, Anne Frances; Orme-Johnson, William H.      Journal of Biological Chemistry  (1992),  267(13),  9398-408.[pdf] 

37. A guide to electron paramagnetic resonance spectroscopy of photosystem II membranes.     Miller, Anne Frances; Brudvig, Gary W.    Biochimica et Biophysica Acta  (1991),  1056(1),  1-18. 

38. Electron-transfer events leading to reconstitution of oxygen-evolution activity in manganese-depleted photosystem II membranes.     Miller, Anne Frances; Brudvig, Gary W.    Biochemistry  (1990),  29(6),  1385-92. [pdf]

39. Characterization of the multiple forms of cytochrome b559 in photosystem II.     Thompson, Lynmarie K.; Miller, Anne Frances; Buser, Carolyn A.; De Paula, Julio C.; Brudvig, Gary W.     Biochemistry  (1989),  28(20),  8048-56. 

40. Manganese and calcium requirements for reconstitution of oxygen-evolution activity in manganese-depleted photosystem II membranes.     Miller, Anne Frances; Brudvig, Gary W.     Biochemistry  (1989),  28(20),  8181-90. 

41. Electron donation in photosystem II.     Thompson, Lynmarie K.; Miller, Anne Frances; De Paula, Julio C.; Brudvig, Gary W.     Israel Journal of Chemistry  (1988),  28(2-3),  121-8. 

42. Formation of the S2 state and structure of the manganese complex in photosystem II lacking the extrinsic 33 kilodalton polypeptide.     Miller, Anne Frances; De Paula, Julio C.; Brudvig, Gary W.      Photosynthesis Research  (1987),  12(3),  205-18. 

43. Effect of the 17- and 23-kilodalton polypeptides, calcium, and chloride and electron transfer in photosystem II.     De Paula, Julio C.; Li, Peter Mark; Miller, Anne Frances; Wu, Brian W.; Brudvig, Gary W.     Biochemistry  (1986),  25(21),  6487-94. 

Web release

http://access.ncsa.uiuc.edu/CoverStories/flavins/

Books

Edited by Albrecht Messerschmidt, Robert Huber, Thomas Poulos and Karl Wieghardt 

© John Wiley & Sons, Ltd, Chichester, 2001

Meeting posters/presentations (**Out of date**)

1. Redox tuning over 600 mV in superoxide dismutase.     Miller, Anne-Frances; Yikilmaz, Emine; Vance, Carrie; Schwartz, Aaron L.; Xie, Juan; Brunold, Thomas C.    Department of Chemistry,  University of Kentucky,  Lexington,  KY,  USA.    Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004  (2004),     INOR-419.

2. Cytochrome b558 (III) from erythrocyte membrane: Some physico-chemical properties.     Karapetyan, Anush; Simonyan, Gagham; Miller, Anne-Frances; Lynn, Bert; Osipyan, Madlen; Simonyan, Ruzan; Simonyan, Maxim.    Chemistry,  University of Kentucky,  Lexington,  KY,  USA.    Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004  (2004),     BIOT-311.

3. Activated flavins and their calculated N(5) NMR shieldings.     Walsh, Joseph D.; Miller, Anne-Frances.    Department of Biophysics and Chemistry,  The Johns Hopkins University,  Baltimore,  MD,  USA.  Editor(s): Chapman, Stephen K.; Perham, Richard N.; Scrutton, Nigel S.    Flavins and Flavoproteins 2002, Proceedings of the International Symposium, 14th, Cambridge, United Kingdom, July 14-18, 2002  (2002),     441-445.

4. A proposed electrostatic contribution to the obligate two-electron, oxygen-insensitive reactivity of enteric nitroreductase.     Miller, Anne-Frances; Koder, Ronald L., Jr.; Walsh, Joseph D.; Haynes, Chad A.; Rodgers, Michael; Erdmann, Helmut; Hecht, Hans-Juergen; Rodgers, David W.    Dept. of Chemistry,  University of KY,  Lexington,  KY,  USA.  Editor(s): Chapman, Stephen K.; Perham, Richard N.; Scrutton, Nigel S.    Flavins and Flavoproteins 2002, Proceedings of the International Symposium, 14th, Cambridge, United Kingdom, July 14-18, 2002  (2002),     293-298.

5. Thermodynamic bases for the obligate two-electron, oxygen-insensitive reactivity of enteric nitroreductase.     Miller, Anne-Frances; Koder, Ronald L., Jr.; Rodgers, Michael E.; Haynes, Chad A.; Rodgers, David W.    Chemistry,  University of Kentucky,  Lexington,  KY,  USA.    Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002  (2002),     BIOL-111.

6. Structure/function studies of iron dependent superoxide dismutase.     Xie, Juan; Yikilmaz, Emine; Miller, Anne-Frances; Brunold, Thomas C.    Department of Chemistry,  University of Wisconsin-Madison,  Madison,  WI,  USA.    Abstracts of Papers, 222nd ACS National Meeting, Chicago, IL, United States, August 26-30, 2001  (2001),     INOR-123.

7. Theoretical destabilization of the flavin semiquinone of Enterobacter cloacae nitroreductase by a hydrogen-bonding-bending mechanism.     Walsh, Joseph D.; Miller, Anne-Frances.    Departments of Biophysics and Chemistry,  The Johns Hopkins University,  Baltimore,  MD,  USA.  Editor(s): Ghisla, Sandro.    Flavins and Flavoproteins 1999, Proceedings of the International Symposium, 13th, Konstanz, Germany, Aug. 29-Sept. 4, 1999  (1999),     63-66.

8. Flavin binding thermodynamics in Enterobacter cloacae nitroreductase.     Koder, Ronald L.; Rodgers, Michael E.; Miller, Anne-Frances.    Departments of Biophysics, Biology and Chemistry,  The Johns Hopkins University,  Baltimore,  MD,  USA.  Editor(s): Ghisla, Sandro.    Flavins and Flavoproteins 1999, Proceedings of the International Symposium, 13th, Konstanz, Germany, Aug. 29-Sept. 4, 1999  (1999),     45-48.

9. The 33 kDa extrinsic polypeptide of photosystem II is not a ligand to manganese in the oxygen evolving complex.     Miller, Anne Frances; De Paula, Julio C.; Brudvig, Gary W.    Dep. Chem.,  Yale Univ.,  New Haven,  CT,  USA.  Editor(s): Biggins, John.    Prog. Photosynth. Res., Proc. Int. Congr. Photosynth., 7th  (1987),  Meeting Date 1986,  1  601-4.