Twenty-Third Annual Symposium on

Chemistry and
Molecular Biology

Established in the memory of Anna S. Naff

Tuesday, April 8, 1997; 8:00 a.m.
Room 139, Chemistry-Physics Building
Department of Chemistry, University of Kentucky

The Role of Combinatorial Chemistry in Drug Design

Hit the clipboard for the Agenda of Program 1997

Hit the clipboard for a registration form for Program 1997

print it and mail it

Featured Speakers

• Arno Spatola (University of Louisville)
  

  Title: "Combinatorial Chemistry: The End of Rational Drug

  Design? Lessons from Macrocyclic Libraries"

  • Basic Combinatorial Methods

  • a Brief Historical Overview

  • a "Realistic" View of the Methods-not a Panacea

  • Why so Much Industrial Attention?

  • Parallel Synthesis vs. Mixtures

  • The Deconvolution Problem

  • Combinatorial Chemistry at the University of Louisville

• Kim Janda (Scripps Institute and Combi Chem)
  

  Title: "From Combinatorics to Soluble Polymer Supported Synthesis"

  • Encoded Combinatorial Chemistry

  • Recursive Deconvolution

  • Liquid Phase Combinatorial Synthesis of peptides,

  • Peptidomimetics, and Small Molecules

  • Multipolymeric Reactions

  • Combizymes

  • Combinatorial Polymer Synthesis

• Jon Ellman (University of California at Berkeley)
  

  Title: "Design, Synthesis, and Evaluation of Small Molecule Libraries"

  • General Philosophy for the Design of Combinatorial Schemes

  • Prudent Selection of Classes of Compounds for Combinatorial Approaches.

  • Heuristic Bioactivity of Known Drugs as Starting Points in Combinatorial Approaches.

  • Synthetic Approaches to Maximize Molecular Diversity

• Dr. Mario Geysen (Glaxo Wellcome Pharmaceuticals)
  
• Dr. Geysen is credited as inventor of combinatorial synthesis.

Title: "Combinatorial Chemistry: A New Paradigm for Drug Discovery."

• Personalized Historical View of Combinatorial Chemistry

• Combinatorial Chemistry: Perspective of the Pharmaceutical Industry

• Combinatorial Chemistry at Glaxo Wellcome.

Parking, directions and info:

Free parking available at Commonwealth Stadium in the "K" designated area on Cooper Drive. Shuttle buses run to the main campus. Additional parking (for a fee) available in UK Medical Plaza Parking Garage, located approximately one block south of the Chemistry-Physics Building; this garage can be accessed from both Rose and Limestone Streets - look for Medical Plaza Parking signs. For additional information, call Professor Art Cammers-Goodwin, Department of Chemistry, (859) 257-7076. Maps of the campus are available online.

1997 Committee: Professor Art Cammers-Goodwin (Chemistry, Committee Chair).

Symposium supported by the Anna S. Naff Endowment Fund

[About the Naff Symposium]   [1996 symposium]   [Other Chemistry seminars]